About

"The most important part of my role is interacting with patients. Every couple – every individual – is unique in their needs, their level of knowledge and their feelings about treatment".

Raj Mathur is a leading national figure in the field of Reproductive Medicine and Surgery. He is a Fellow of the Royal College of Obstetricans and Gynaecologists and has Subspeciality Accreditation in Reproductive Medicine and Surgery. He has been a Consultant Gynaecologist at Addenbrooke's Hospital in Cambridge since 2003. Raj trained under some of the best known pioneers in fertility treatment in the UK – Professor Ian Cooke in Sheffield and the late Professor Mike Hull in Bristol, and then spent five years carrying out IVF at Bristol University Centre for Reproductive Medicine, including research that led to him being awarded the degree of M.D. by Bristol University. He then went on to do a two-year accredited subspecialty programme in Reproductive Medicine and Surgery at Cambridge.

He has played a key role in developing leading-edge fertility treatments in Cambridge, and is lead consultant for Cambridge IVF. He is a member of the Executive Committee of the British Fertility Society. 

In addition to Fertility, Raj also provides surgical and medical treatment for patients with endometriosis and pelvic pain and general gynaecological problems such as fibroids and ovarian cysts. He is accredited to perform laparoscopic surgery and endometrial ablation. He is a leading expert in ovarian hyperstimulation syndrome (OHSS) and why some women are prone to this condition.

Of his work in the area of Fertility, Raj says: “The most important part of my role is interacting with patients. Every couple – every individual – is unique in their needs, their level of knowledge and their feelings about fertility treatment. It’s my job to individualise treatment to suit your particular circumstances while offering advice that is based on good quality evidence and my knowledge of the latest research. My priority is to help you have a healthy baby“.

Raj is media spokesman for the British Fertility Society, which keeps him up-to-date with all the latest advances, in turn enabling him to give patients the best possible advice. His highly specialised training and research gives him the skills to manage complex cases and referrals from across the east of England.

Raj regularly writes for professional journals and is frequently invited to lecture at educational meetings both in the UK and overseas. He has a special interest in the safety of IVF treatment and also wrote the Royal College guidelines on managing ovarian hyperstimulation syndrome. He is programme director for the Subspeciality Training Programme in Reproductive Medicine at Cambridge.

Professional associations

Selected publications

Several articles are available online. Please email if you would like a reprint - we will oblige where we can!

Tan B, Mathur R (2013) Management of Ovarian Hyperstimulation Syndrome Human Fertility in press

Tan B, Mathur R, on behalf of the British Fertility Society Policy and Practice Subcommittee (2013) Management of OHSS guidelines Human Fertility in press

Prakash A, Mathur RS (2013) Ovarian Hyperstimulation Syndrome. The Obstetrician and Gynaecologist Vol 15, 31-35

Prasannan-Nair, Manis T,  Mathur R (2010) Management of endometriosis-associated infertility TOG Vol 13, 1-6

Palep-Singh M, Angala P, Seela R, Mathur R (2007) Impact of microwave endometrial ablation in the management of subsequent unplanned pregnancy J Minim Invasive Gynecol. 14(3):365-6.

Pashayan N, Lyriatzopoulos G, Mathur R (2006) Cost-effectiveness of primary offer of IVF vs. primary offer of IUI followed by IVF (for IUI failures) in couples with unexplained or mild male factor subfertility. BMC Health Services Research 2006, 6:80     doi:10.1186/1472-6963-6-80

Mathur RS, Hayman G, Bansal AS, Jenkins JM (2002) Serum Vascular Endothelial Growth Factor levels in highly responsive women are poorly predictive of subsequent Ovarian Hyperstimulation Syndrome. Fertility and Sterility 78, 1154-1158.

Mathur RS, Akande AV, Keay SD, Hunt LP, Jenkins JM (2000) Distinction between early and late OHSS. Fertility and Sterility 73, 901-912.

Emovon E, Mathur RS, Wilson P, Ashcroft S A, Jenkins JM, Gordon U D (2000) Norethisterone cotreatment with buserelin is associated with a low incidence of functional ovarian cysts. Reproductive Technologies, 10, 206-209.

Smith MP, Mathur RS, Keay SD, Hall L, Hull MGR, Jenkins JM (2000). Periovulatory human oocytes, cumulus cells and ovarian leukocytes express type 1 but not type 2 11 bhydroxysteroid dehydrogenase RNA. Fertility and Sterility, 73, 825 – 830.

Mathur RS, Joels LA, Jenkins JM (1995) Ovarian hyperstimulation syndrome may be more likely if multiple pregnancy follows assisted conception. Acta geneticae medicae et gemellologiae 44; 233-235.

Lloyd-Williams, Jenkins JM, Mathur RS, Cooke ID, Morris HJ (1994) Knowledge discovery in an infertility database using artificial neural networks. Proceedings of the Institute of Electrical Engineers.

Prakash A, Karasu T, Mathur R (2009) Ovarian hyperstimulation syndrome: pathophysiology, prevention and management. Obstetrics, Gynaecology and Reproductive Medicine (2009), doi:10.1016/j.ogrm.2009.05.003

Mathur R, Sumaya W (2007) Prevention and management of ovarian hyperstimulation syndrome. Obstetrics, Gynaecology and Reproductive Medicine. 18; 18-22

Mathur R, Kailasam C, Jenkins JM (2007) The evidence base of strategies for the prevention of OHSS. Human Fertility 10(2); 75-85

Park S-M, Mathur R, Smith GCS (2006) Congenital anomalies after treatment for infertility. BMJ 333; 665-6

Mathur R, Smith SK (2002) Endometrial angiogenesis – physiology and clinical implications. Journal of Family Planning and Reproductive Health Care, 28, 173-174.

Mathur RS, Evbuomwan I, Jenkins JM (2002) Prevention and management of OHSS. Current Obstetrics and Gynaecology, 12, 111-116.

Mathur RS, Jenkins JM (2001) Ovarian hyperstimulation Syndrome: an endocrinopathy? Current Opinion in Obstetrics and Gynaecology 13, 329-333

Mathur RS, Jenkins JM (2000) Is Ovarian Hyperstimulation Syndrome associated with poor obstetric outcome? British Journal of Obstetrics and Gynaecology, 107, 943-946.

Mathur RS, Jenkins JM (1999). Patients should be allowed to choose between the morbidity of OHSS and the benefits of parenthood. Human Reproduction, 14, 2183 – 2185.

Mathur RS, Hull MGR (1998) Ovarian hyperstimulation syndrome in early pregnancy. RCOG Dialogue.

Jenkins JM, Mathur RS (1998) Management of ovarian hyperstimulation syndrome. RCOG PACE review.

Mathur RS, Jenkins JM, Bansal AS (1997) The possible role of the immune system in the aetiopathogenesis of ovarian hyperstimulation syndrome. Human Reproduction 12, 2629 – 2634

Jenkins JM, Missou H, Mathur RS (1997) ReproMed - an interactive guide to Reproductive Medicine. Interact, 14, 16.

Ford WCL, Mathur RS, Hull MGR (1997) Intra-uterine insemination for male infertility: is it effective treatment? In Baillieres Clinical Obstetrics and Gynaecology Male Infertility, Eds. van Steirteghem A, Tournaye H, Devroey P 691 – 710.

Keay SD, Liversidge NH, Mathur RS, Jenkins JM (1997) Assisted conception following poor ovarian response to gonadotrophin stimulation. British Journal of Obstetrics and Gynaecology 104; 521 – 527.

Mathur RS, Joels LA, Akande AV, Jenkins JM (1996) Prevention of ovarian hyperstimulation syndrome. British Journal of Obstetrics and Gynaecology 103; 740-746.

Akande AV, Mathur RS, Keay SD, Jenkins JM (1996) The choice of luteal support following pituitary downregulation, controlled ovarian hyperstimulation and in vitro fertilization. British Journal of Obstetrics and Gynaecology 103; 963 – 966.

Jenkins JM, Mathur RS, Cooke ID (1995) Management of severe ovarian hyperstimulation syndrome. British Journal of Obstetrics and Gynaecology 102; 2-5.

Duncan WC, Jenkins JM, Mathur RS, Li TC (1994) Induction of ovulation by human menopausal gonadotrophins. Contemporary reviews in Obstetrics and Gynaecology 6; 154-160

Mathur R, Jenkins JM (2009) Towards a clinically useful classification of OHSS RBM Online
Vol 19. No 3. 2009 434 www.rbmonline.com/Article/4619 on web 11 August 2009

Choong CK, Calvert PA, Falter F, Mathur R, Appleton D, Wells FC, Schofield PM, Crawford R (2008) Life Threatening Impending Paradoxical Embolus Caught Red Handed: Successful Management By Multidisciplinary Team Approach Journal of Thoracic and Cardiovascular Surgery (in press)

Mathur RS, Jenkins JM (2000) Selection of controls for study of pregnancy outcome in cycles complicated by OHSS. Fertility and Sterility 73, 123.

Mathur RS, Oumachigui A (1991) Squamous cell carcinoma cervix with mucinous cystadenocarcinoma of the ovary - a Case Report. Journal of Gynaecology and Obstetrics of India 41; 429.

Mathur RS (2011) Investigation of infertility and making a diagnosis. ESHRE course for junior doctors and paramedics, St Petersburg

Mathur RS (2011) Special cases – PCOS, poor responders. ESHRE course for junior doctors and paramedics, St Petersburg

Mathur RS (2011) Ovarian Hyperstimulation Syndrome. ESHRE course for junior doctors and paramedics, St Petersburg

Mathur RS (2008) Prevention and management of OHSS. RCOG

Mathur RS (2008) Prevention and management of Ovarian Hyperstimulation Syndrome. International Society of Mild Approaches in Assisted Reproduction meeting, London.

Mathur RS (2007) Prevention and management of OHSS. Senior Staff Conference, RCOG London

Mathur RS (2006) Ovarian stimulation regimes. International Federation of Fertility Societies meeting, Hanoi

Mathur RS (2005) IUI after NICE – a role for cautious ovarian stimulation? Presented at the BFS annual meeting, Warwick.

Mathur RS (2005) International variation in management of OHSS. Presented at Serono Symposium on international variation in assisted reproduction practice and data collection, Athens.

Prentice A, Mathur RS, Morton N (2001) Superovulation improves pregnancy rates in women who fail to conceive with donor insemination alone. Presented at the IFFS meeting, Melbourne, November 2001.

Mathur RS, Hayman G, Bansal AS, Jenkins JM (2001) Serum Vascular Endothelial Growth Factor levels in highly responsive women are poorly predictive of subsequent Ovarian Hyperstimulation Syndrome. Presented at the annual meeting of the BFS, Belfast, April 2001. 

Mathur RS, Bansal AS, Jenkins JM (2000) Follicular fluid Vascular Endothelial Growth Factor (VEGF) levels in highly responsive women who subsequently develop Ovarian Hyperstimulation Syndrome (OHSS) are lower than levels in matched controls – a pilot study. Presented at the winter meeting of the BFS, London, December 2000.

Mathur RS, Jenkins JM (2000) Obstetric outcome of pregnancies complicated by OHSS. Presented at the winter meeting of the BFS, Bath, January 2000.

Mathur RS, Hunt LP, Hull MGR, Jenkins JM (1999) OHSS in women undergoing assisted conception occurs in two distinct forms. Presented at the Blair Bell Research Society Competition Meeting, RCOG, London.

Mathur RS, Akande AV, Jenkins JM (1999) The occurrence of OHSS is not determined by early luteal serum hCG levels. Presented at the 15th Annual meeting of ESHRE, Tours, France.

Mathur RS, Ashcroft SA, Smith MP, Jenkins JM (1998) Functional ovarian cysts seldom occur following Gonadotrophin releasing hormone agonist with norethisterone co-treatment prior to IVF. Presented at the British Fertility Society  (BFS) annual meeting, Sheffield.

Keay SD, Mathur RS, Akande AV, Jenkins JM (1998) Basal serum Insulin-like Growth Factor 1 concentrations are poorly predictive of ovarian response to gonadotrophin stimulation. Presented at the BFS annual meeting, Sheffield.

Akande AV, Keay SD, Mathur RS, Jenkins JM, Hull MGR (1998) Luteal phase serum progesterone levels are poor predictors of pregnancy after IVF or GIFT treatment. Presented at the BFS annual meeting, Sheffield.

Keay SD, Mathur RS, Jenkins JM (1998) Glucocorticoid cotreatment reduces cycle cancellation due to poor ovarian response in stimulated IVF cycles. Presented at the National Ovarian Workshop, Bristol.

Mathur RS, Akande AV, Keay SD, Harbottle SJ, Jenkins JM (1997) Late onset Ovarian Hyperstimulation Syndrome in women undergoing assisted conception is poorly predicted by peak oestradiol levels and number of eggs obtained. Presented at the annual conference of ESHRE, Edinburgh.

Mathur RS, Akande AV, Sowter M, Gordon UD, Jenkins JM, Hull MGR (1997) The antecedents of early versus late Ovarian Hyperstimulation Syndrome in women undergoing assisted conception. Presented at the Joint Fertility Societies Meeting, York.

Akande AV, Keay SD, Mathur RS, Sowter M (1997) The practical implication of a raised basal serum FSH level on the chance of poor ovarian response and cancellation of IVF treatment. Presented at the Joint Fertility Societies Meeting, York.

Keay SD, Liversidge NH, Mathur RS, Jenkins JM (1997) Ovarian follicular capacity indicated by the response to administered gonadotrophin relates to the ability of the resulting embryos to implant. Presented at the Joint Fertility Societies Meeting, York.

Mathur RS, Joels LA, Jenkins JM (1996) Ovarian Hyperstimulation Syndrome may be more likely if multiple pregnancy follows assisted conception. Presented at the 3rd International meeting of the RCOG, New Delhi, India.

Keay SD, Rennie A, Liversedge NH, Mathur RS, Akande V, Jenkins JM (1996) Reliability of IVF databases - suggestions for improvements. Presented at the winter meeting of the BFS, Cardiff.

Mathur RS, Duncan WC, Casey SF, Jenkins JM, Cooke ID (1995) Low dose gonadotrophin therapy to improve pregnancy rates in women who fail to conceive with donor insemination alone. Presented at the British Congress of Obstetrics and Gynaecology, Dublin.